Table 1.
Relationship between Bcl-2 and survivin expression and patient characteristics
| Patient characteristic | Total | Bcl-2- | Bcl-2+ | p | Survivin- | Survivin+ | P | Bcl-2-Survivin- | non-Bcl-2-Survivin- | p |
|---|---|---|---|---|---|---|---|---|---|---|
| No. patients (%) | 45 | 10 (22) | 35 (88) | 26 (58) | 19 (42) | 7 (16) | 38 (84) | |||
| Age ≥ 60 y, no. (%) | 15 | 6 (40) | 9 (60) | 0.062 | 8 (53) | 7 (47) | 0.754 | 4 (27) | 11 (73) | 0.199 |
| Male, no. (%) | 28 | 6 (21) | 22 (79) | 1 | 16 (57) | 12 (43) | 1 | 4 (14) | 24 (86) | 1 |
| Hb ≤ 85 g/l, no. (%) | 28 | 5 (18) | 23 (82) | 0.467 | 14 (50) | 14 (50) | 0.222 | 4 (14) | 24 (86) | 1 |
| sCalcium ≥ 2.65 mmol/l, no. (%) | 10 | 4 (40) | 6 (60) | 0.194 | 5 (50) | 5 (50) | 0.72 | 3 (30) | 7 (70) | 0.172 |
| Advanced LBD, no. (%) | 22 | 5 (23) | 17 (77) | 1 | 15 (68) | 7 (32) | 0.231 | 3 (14) | 19 (86) | 1 |
| sCR ≥ 177 mmol/l, no. (%) | 19 | 5 (26) | 14 (74) | 0.72 | 11 (58) | 8 (42) | 1 | 2 (11) | 17 (89) | 0.681 |
| Stage III (DS), no. (%) | 32 | 5 (16) | 27 (84) | 0.111 | 17 (53) | 15 (47) | 0.504 | 4 (13) | 28 (87) | 0.655 |
| Stage III (ISS), no. (%) | 27 | 6 (22) | 21 (78) | 0.561 | 16 (59) | 11 (41) | 0.554 | 5 (19) | 22 (81) | 0.77 |
Abbreviation: Hb, hemoglobin; LBD, lytic bone disease; sCR, serum creatinine; DS, Durie-Salmon staging system; ISS, International Staging System.