Table 2.

Relationship between Bcl-2 and survivin expression and treatment response

	Treatment	No. patients	CR + PR, no. (%)	P
Total	Bor	16	14 (87.5)
	non-bor	29	7 (24)	< 0.001
Bcl-2-	Bor	4	4 (100)
	non-bor	6	2 (33)	0.076
Bcl-2+	Bor	12	10 (83)
	non-bor	23	5 (22)	0.001
Survivin-	Bor	9	7 (78)
	non-bor	17	6 (35)	0.097
Survivin+	Bor	7	7 (100)
	non-bor	12	1 (8)	< 0.001
Bcl-2-Survivin-	Bor	2	2 (100)
	non-bor	5	2 (40)	0.429
non-Bcl-2-Survivin-	Bor	14	12 (86)
	non-bor	24	5 (21)	< 0.001

Abbreviations: Bor, bortezomib; CR, complete response; PR, partial response.