Table 2.
Sensitivity, specificity, PPV and NPV of markers used in this study [% (positive/total stained)]
| Marker | Subtype | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|
| ΔNp63 | SCC | 100 (16/16) | 100 (32/32) | 100 (16/16) | 100 (32/32) |
| p63 | SCC | 100 (16/16) | 88 (28/32) | 80 (16/20) | 100 (28/28) |
| CK5/6 | SCC | 81 (13/16) | 100 (32/32) | 100 (13/13) | 91 (32/35) |
| 34βE12 | SCC | 94 (15/16) | 47 (15/32) | 47 (15/32) | 94 (15/16) |
| TTF1 | AC | 80 (20/25) | 87 (20/23) | 87 (20/23) | 80 (20/25) |
| Napsin A | AC | 64 (16/25) | 100 (23/23) | 100 (16/16) | 72 (23/32) |
| CK7 | AC | 100 (25/25) | 35 (8/23) | 63 (25/40) | 100 (8/8) |
| CK8/18 | AC | 100 (25/25) | 35 (8/23) | 63 (25/40) | 100 (8/8) |
Sensitivity = TP/TP+FN; Specificity = TN/TN+FP; Positive predictive value (PPV) = TP/TP+FP; Negative predictive value (NPV) = TN/TN+FN. FN indicates false negatives; FP, false positives; TN, true negatives; TP, true positives.