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Immunohistochemical analysis of HCL and its mimics
| Diagnosis | No of Cases | Tissue/Organ | BRAF V600E (% positive) |
|---|---|---|---|
| HCL | 12 | Bone marrow | 100% |
| HCL-v | 3 | Bone marrow (n=2); Spleen (n=1) | 0% |
| SMZL | 6 | Spleen | 0% |
| MALT | 4 | Parotid (n=3); Stomach (n=1) | 0% |
| MZL | 3 | Lymph node (n=1); Bone marrow (n=2) | 0% |
HCL: Hairy cell leukemia; HCL-v: HCL variant; SMZL: Splenic marginal zone lymphoma; MZL: nodal Marginal zone lymphoma; MALT: extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue.
