Table 2.

Clinical Features in 7 Patients with BPDCN

Case NO.	Sex/Age	Clinical presentations	Initial Location	Size (cm)	CCD4	CCD43	CCD56	CCD123	Therapy	Follow-up	References
1	M/69	‘bruise-like’ patches	the chest and left shoulder	NA	+	+	+	+	CVAD andallo-HCT	6 months	[15]
2	M/74	nodular lesions only	left shoulder	5 × 3	+	NA	+	+	low-dose DeVIC and radiation therapy	Sustained complete remission	[16]
3	F/79	disseminated lesions (patches and nodules)	the back	3 × 4	+	NA	+	+	palliative care	8 months	[17]
4	M/74	‘bruise-like’ patches	the face	NA	+	NA	+	+	palliative chemotherapy with cytarabine and mitoxantrone	4 months	[18]
5	M/67	nodular lesions only	the back	NA	+	+	+	NA	six courses of multidrug chemotherapy consisting of ifosphamide, methotrexed, etoposide, prednisoloneandL-asparaginase,	partial remission	[19]
6	M/36	‘bruise-like’ patches	the trunk and extremities	NA	+	+	+	NA	prednisone 30 mg/day, radiotherapy and bone marrow transplantation	Sustained complete remission	[20]
7	M/76	nodular lesions only	the face and scalp	7 × 7	+	+	+	+	Six cycles of CHOP	7 months	[21]

Abbreviations: CVAD: hyper-central venous access devices; allo-HCT: allogeneic stem cell transplant; DeVICtherapy: consists of non-multi-drug-resistance (MDR)-associated drugs (dexamethasone ifosphamide, and carboplatin), and etoposide; CHOP: cyclophosphamide, adryamicin, vincristine, and prednisolone. NA: not available.