Table 1.
Case reports of ectopic cortisol-producing adrenocortical adenoma
| Case | Publishing time | Sex/Age (y/o) | Largest diameter of the tumor (cm) | Tumor location | Cortisol level in tissue homogenate | Enzyme profile | Ultrastructure | |
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Immunostaining | mRNA expression | |||||||
| 1 | 1998 [1] | F/33 | 3.0 | Next to left adrenal | ND | ND | ND | ND |
| 2 | 2000 [2] | F/63 | 3.5 | Left renal hilum | ND | ND | ND | ND |
| 3 | 2010 [3] | F/35 | 3.8 | Left pararenal | ND | CYP17A1 (+) CYP21 (+) | CYP11B1 mRNA is higher in ectopic CPA than that in normal adrenal | ND |
| 4 | 2012 [4] | M/38 | 5.3 | Anterior of left renal hilum | ND | ND | ND | ND |
| ours | 2014 | F/53 | 3.5 | Left renal hilum | Similar to adrenal CPA | CYP17A1 (+) HSD3B2 (+) | Expression pattern for CYP11B1, CYP11B2, CYP17A1 and HSD3B2 mRNA in the ectopic CPA was similar to that in adrenal CPA | The tumor was composed of compact cells which had numerous organelles, as well as clear cells which contained large clumps of lipid droplets and less organelles |
ND: Not described.