Table 3.

Multivariate analyses for progression-free survival and overall survival by Cox regression model

	Progression-free survival			Overall survival
Variable	Hazard ratio	95% CI	P-value	Hazard ratio	95% CI	P-value
Age (years)	0.91	0.45-1.89	0.56	1.22	0.23-2.81	0.61
Gender	0.69	0.25-3.27	0.69	0.97	0.48-3.11	0.34
Smoking history	1.47	0.89-7.28	0.09	1.83	0.72-8.77	0.07
Weight loss	1.38	0.77-4.81	0.12	1.69	0.79-4.99	0.08
TNM stage	4.28	3.11-16.2	0.001	3.37	2.21-18.91	0.004
Regional lymph node involvement	2.11	1.39-5.31	0.01	1.24	0.92-2.49	0.07
Histology	1.27	0.79-2.97	0.57	0.93	0.49-1.28	0.48
Differentiation	3.82	0.73-14.78	0.06	4.77	3.62-16.46	<0.001
Surgical margins	2.09	1.88-4.85	0.04	1.63	0.73-6.63	0.06
MiR-107	3.08	2.01-8.92	0.003	2.57	1.88-10.28	0.007