[Table/Fig-4]:

Published clinical studies on combination of antibiotic therapy in-hospitalized patients with CAP

Author	Cohort	Study design	n	Drug Combination	Outcome
Weiss et al., [8]	Pneumococcal bacteremia	Monocenter, retrospective	95	β-lactam plus macrolide	Lower mortality with combination
Dudas et al., [15]	CAP	Multicenter, prospective	2963	β-lactam plus macrolide	Lower mortality and reduced length of stay
Waterer et al., [16]	Pneumococcal bacteremia	Multicenter, retrospective	225	β-lactam plus macrolide	Lower mortality
Lodies TP et al., [17]	CAP	Multicenter, retrospective	845	β-lactam plus macrolide	Lower mortality
Rodrigo C et al., [18]	CAP	Multicenter, retropective	5240	β-lactam plus macrolide	Lower mortality