[Table/Fig-10]:
Genotype and allele frequencies of IL 18-607 polymorphism in rheumatoid arthritis patients in relation to clinical features
| Geno type / allele | Morning Stiffness | Rheumatoid Factor | Age of onset | Gender | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| <1 (n=46) | >1 (n=18) | p-value | Significance | Positive (n=34) | Negative (n=30) | p-value | Significance | >35 years (n=47) | <35 years (n=25) | p-value | Significance | Females (n=46) | Males (n=19) | p-value | Significance | |||||||||
| n | % | n | % | n | % | n | % | n | % | n | % | n | % | n | % | |||||||||
| AA | 1 | 2.17 | 1 | 5.55 | 0.484 | NS | 1 | 2.94 | 1 | 3.33 | 0.928 | NS | 6 | 12.76 | 4 | 16.0 | 0.705 | NS | 2 | 4.34 | 1 | 5.26 | 0.872 | NS |
| CA | 22 | 47.82 | 8 | 44.44 | 0.807 | NS | 13 | 38.23 | 17 | 56.66 | 0.140 | NS | 23 | 48.93 | 7 | 28.0 | 0.086 | NS | 22 | 47.28 | 8 | 42.10 | 0.673 | NS |
| CC | 23 | 50.0 | 9 | 50.0 | 1.000 | NS | 20 | 58.82 | 12 | 40.0 | 0.132 | NS | 18 | 38.29 | 14 | 56.0 | 0.150 | NS | 22 | 47.28 | 10 | 52.63 | 0.724 | NS |
| A-allele | 24 | 26.08 | 10 | 27.77 | 0.845 | NS | 15 | 22.05 | 19 | 31.66 | 0.219 | NS | 35 | 37.23 | 15 | 30.0 | 0.385 | NS | 26 | 28.62 | 10 | 26.13 | 0.821 | NS |
| C-allele | 68 | 73.91 | 26 | 72.22 | 0.845 | NS | 53 | 77.94 | 41 | 68.33 | 0.219 | NS | 59 | 62.76 | 35 | 70.0 | 0.385 | NS | 66 | 71.73 | 28 | 73.68 | 0.821 | NS |
n – number of patients, <1 =less than one hour, >1 = more than one hour, <35 = less than 35 years, >35 =more than 35 years, p-value = probability value of the statistical test, S = significant, NS = not significant