[Table/Fig-2]:
Comparison of markers ofatherosclerosis measured by oscillometricmethods across four studygroups(expressed as median, minimum and maximum)
| Parameter | Group A-I (n= 55) | Group A-II (n=28) | Group B-I (n= 31) | Group B-II (n=30) | Overall p-value (Post-hoc p-value after Bonferroni’s Correction) | |
|---|---|---|---|---|---|---|
| Vascular age years | 71 (40, 90) | 57.5 (36, 90) | 61 (39, 90) | 50 (30, 90) | 0.005 (a: 0.01, c: 0.001) | |
| Pulse pressure mmHg | 64 (43,113) | 59 (42, 93) | 66 (43,96) | 55.5 (37, 76) | 0.005 (c: 0.001, f: 0.001) | |
| PWV | Right brachial-ankle- cm/s | 1505 (-1810,5562) | 1332 (-1400,24145) | 1387 (-1863, 2764) | 1286 (950, 12479) | 0.02 (a: 0.04, b: 0.03, c: 0.004) |
| Left brachial-ankle -cm/s | 1686 (-7378, 6617) | 1335 (-44431,55295) | 1522 (1155, 4224) | 1301 (-13792, 5683) | 0.007 (a: 0.004, c: 0.01) | |
| Carotid-femoral PWV -cm/s | 1105 (113, 24567) | 953 (660, 24868) | 1019 (714, 2466) | 857 (483, 10165) | 0.03 (c: 0.006) | |
| ASI | Right brachial ASI -mmHg | 31.6 (14, 62.6) | 28 (-52, 1052) | 28 (13.6, 55.3) | 25.3 (-14.8, 40.4) | 0.01 (c: 0.001, f: 0.03) |
| Left brachial ASI -mmHg | 30.8 (3.6, 73.8) | 29.2 (-35.6, 47) | 30.2 (15.6, 53.2) | 27 (12, 42) | 0.04 (c: 0.01, f: 0.05) | |
| Right ankle ASI -mmHg | 41.6 (19.8, 83.4) | 33.2 (0, 74) | 37.4 (27, 61.8) | 36.9 (20.2, 56.2) | 0.007 (a: 0.005, d: 0.03) | |
| Left ankle ASI -mmHg | 47.8 (20.8, 77.2) | 32.7 (0, 70.6) | 38.8 (24.4, 57.8) | 36 (16.6, 50) | <0.001 (a: 0.001,b: 0.01, c: < 0.001, d: 0.01) | |
| ABI | Right ABI | 1.11 (0.84, 1.26) | 1.1 (0.84, 23.8) | 1.11 (0.88, 1.56) | 1.11 (0.82, 1.2) | 0.86 |
| Left ABI | 1.11 (0.98, 1.31) | 1.09 (0.91, 1.27) | 1.11 (0.9, 1.26) | 1.1 (0.78, 1.22) | 0.62 | |
| Aortic pulse pressure-mmHg | 46 (26, 106) | 41 (24, 110) | 44 (25, 75) | 36 (19, 63) | 0.002 (c: 0.00, f: 0.005) | |
| Augmentation index % | 28 (7, 60) | 22 (2, 60) | 25 (7, 52) | 17.5 (-6, 99) | 0.003 (a: 0.01, c: 0.001, f: 0.03) | |
PWV- pulse wave velocity, ASI- arterial stiffness index, ABI- ankle brachial index
a: Patients with diabetes mellitus (>5 years) along with hypertension vs newly diagnosed patients with DM without hypertension
b: Patients with diabetes mellitus (>5 years) along with hypertension vs patients with hypertension
c: Patients with diabetes mellitus (>5 years) along with hypertension vs healthy controls
d: Newly diagnosed patients with DM without hypertension vs patients with hypertension
e: Newly diagnosed patients with DM without hypertension vs healthy controls
f: Patients with hypertension vs healthy controls