Table 2.
Selected Overlap between pQTLs and GWAS SNPs
Trait | SNP | PMID | Chr | Protein | p Value |
---|---|---|---|---|---|
Conduct disorder (case status) | rs2184898 | 20585324 | 10 | PRDM2 | 1.44 × 10−8 |
LDL cholesterol | rs2738459 | 20864672 | 19 | ZNF207 | 1.32 × 10−7 |
Metabolic syndrome (bivariate traits) | rs320 | 21386085 | 8 | ZMYND11 | 4.88 × 10−7 |
Platelet aggregation | rs1659838 | 20526338 | 10 | ZMYND11 | 5.55 × 10−7 |
HIV-1 viral setpoint | rs6997496 | 22174851 | 8 | FAK | 1.15 × 10−6 |
Leprosy | rs10792430 | 22019778 | 11 | OSR1 | 1.37 × 10−6 |
Primary biliary cirrhosis | rs10792430 | 21399635 | 11 | OSR1 | 1.37 × 10−6 |
Blood pressure | rs17417407 | 21909110 | 10 | TWIST1 | 1.39 × 10−6 |
Response to interferon beta therapy | rs9272105 | 21502966 | 6 | SRC | 1.44 × 10−6 |
Cytomegalovirus antibody response | rs931547 | 21993531 | 1 | NCKAP1L | 2.24 × 10−6 |
LDL cholesterol | rs4971544 | 21059979 | 2 | NKX3-2 | 2.33 × 10−6 |
Cytomegalovirus antibody response | rs211228 | 21993531 | 6 | MYST4 | 2.80 × 10−6 |