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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Stroke. 2014 Jul 10;45(8):2485–2487. doi: 10.1161/STROKEAHA.114.005551

Figure 2.

Figure 2

α4 integrin blocking diminishes acute neuroinflammation. A, Concentrations of T cells, neutrophils, and inflammatory monocytes were unchanged in blood 2 days after antibody treatment. N=8–9. B, α4 blockade decreased T cell and inflammatory monocyte recruitment at day 2, but not day 7. Representative flow cytometry plots depict CD4 and CD8 T cells; Ly6G+ neutrophils; and Ly6Chi inflammatory monocytes at day 2. N=5–9. C, Anti-α4-treated mice displayed improved left forelimb use in the cylinder test. N=7–9. **p<0.01 by t test; #p<0.05 by U test; bars indicate mean ± SEM.