Skip to main content
. Author manuscript; available in PMC: 2015 Feb 11.
Published in final edited form as: Nat Commun. 2014 Aug 11;5:4587. doi: 10.1038/ncomms5587

Figure 2. Dynein processivity requires a single motor domain.

Figure 2

(a) Possible ring-ring communication between the two heads is abolished by replacing one of the monomers with a SRS-MTBD chimera. (b) A kymograph of SRS85:82/WT showing that it moves processively along MTs (c) The average velocity (± SD) and run length (± 95% CI) of the SRS-MTBD/WT constructs compared to WT/WT. (d) An example high-resolution tracking trace (black) and stepping fit (red) of the SRS85:82 head. (e) Histograms of the step sizes for the SRS (upper) and WT (lower) heads (mean ± SD).