Table 2.
Expression of IHC markers by diagnosed histological type of testicular tumor
| Histological type of tumor |
Necropsy group |
Biopsy group |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| c-KIT positive tumors/% | % of c-KIT positive cells | PLAP positive tumors/% | % of PLAP positive cells | Cytokeratin positive tumors/% | % of Cytokeratin positive cells | CD 30 positive tumors/% | % of CD 30 positive cells | c-KIT positive tumors/% | % of c-KIT positive cells | PLAP positive tumors/% | % of PLAP positive cells | Cytokeratin positive tumors/% | % of Cytokeratin positive cells | CD 30 positive tumors/% | % of CD 30 positive cells | |
| SIMPLE TUMORS (∑) |
11 |
39 |
23 |
<5 |
27 |
19 |
7 |
8 |
22 |
40 |
27 |
<6 |
33 |
43 |
8 |
23 |
| MIXED TUMORS (∑) |
33 |
23 |
25 |
<5 |
66 |
25 |
8 |
5 |
44 |
26 |
22 |
<7 |
44 |
46 |
11 |
30 |
|
LCT simple |
5 |
5 |
21 |
<5 |
15 |
16 |
5 |
10 |
0 |
0 |
16 |
<5 |
20 |
60 |
6 |
30 |
| with SCT |
20 |
20 |
40 |
<5 |
60 |
23 |
20 |
5 |
0 |
0 |
0 |
0 |
100 |
50 |
0 |
0 |
| with IT SEM |
33 |
10 |
0 |
0 |
60 |
17 |
0 |
0 |
100 |
20 |
100 |
10 |
100 |
5 |
0 |
0 |
| with DIF SEM |
50 |
60 |
0 |
0 |
40 |
40 |
0 |
0 |
75 |
28 |
0 |
0 |
0 |
0 |
0 |
|
|
SCT simple |
0 |
0 |
28 |
<5 |
71 |
32 |
14 |
10 |
6 |
5 |
31 |
<5 |
62 |
51 |
12 |
27 |
| with LCT |
20 |
20 |
40 |
<5 |
60 |
23 |
20 |
5 |
0 |
0 |
0 |
0 |
100 |
50 |
0 |
0 |
| with DIF SEM |
50 |
5 |
50 |
5 |
100 |
30 |
0 |
0 |
0 |
0 |
25 |
5 |
50 |
65 |
25 |
30 |
|
IT SEM simple |
14 |
5 |
14 |
5 |
28 |
5 |
0 |
0 |
0 |
0 |
33 |
10 |
33 |
5 |
0 |
0 |
| with LCT |
33 |
10 |
0 |
0 |
60 |
17 |
0 |
0 |
100 |
20 |
100 |
10 |
100 |
5 |
0 |
0 |
|
DIF SEM simple |
50 |
90 |
25 |
5 |
25 |
5 |
25 |
5 |
45 |
43 |
15 |
11 |
10 |
12 |
0 |
0 |
| with SCT |
50 |
5 |
50 |
5 |
100 |
30 |
0 |
0 |
0 |
0 |
25 |
5 |
50 |
65 |
25 |
30 |
| with LCT |
50 |
60 |
0 |
0 |
40 |
40 |
0 |
0 |
75 |
28 |
0 |
0 |
0 |
0 |
0 |
|
| PNST |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| TERAT |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
20 |
0 |
<5 |
100 |
50 |
100 |
10 |
| IGCNU |
16 |
|
33 |
<5 |
16 |
5 |
0 |
0 |
0 |
0 |
100 |
5 |
0 |
0 |
0 |
0 |
| MET. T. LYMPH |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| Total | 16 | 32 | 23 | <5 | 35 | 21 | 7 | 7 | 26 | 36 | 26 | <6 | 29 | 44 | 8 | 25 |
Note: ∑, sum; DIF SEM, diffuse seminoma; IGCNU, intratubular germ cell neoplasia of undifferentiated origin; IT SEM, intratubular seminoma; LCT, Leydig cell tumors; MET. T. LYMPH, metastatic tumor – lymphoma; PLAP, placental alkaline phosphatase; PNST, peripheral nerve sheat tumor; SCT, Sertoli cell tumor; TERAT, teratoma.