Figure 4.

The attachment probabilities to different binding sites. (A and B) Tightly coupled dimers. (A) Binding site distance distributions for the left (red) and right (green) head and for four possible linker configurations; D denotes the post- and D^∗ the prestroke state. (B) An illustration of the steps taken by the left or the right head. The cylinders correspond to the probability to make a step to the given position; only the most probable steps are depicted. The head that is to make the step (transparent) is in the prestroke position and the other one is in the poststroke. (C and D) Loosely coupled dimers. Binding site distance distributions (C) and the corresponding illustration of steps (D). (E and F) Binding site distance distributions for steps taken by left/right head of stalk length mutants, l = 19 nm (E) and l = 5 nm (F). To see this figure in color, go online.