TABLE 5.
Cox Proportional Hazards Model for the Determination of Independent Factors Affecting Survival for All MDC
| Factor | P | Hazard Ratio |
95% CI |
|
|---|---|---|---|---|
| Upper | Lower | |||
| Age | <0.001 1.09 | 1.05 | 1.13 | |
| Sex | >0.05 | – | – | – |
| Race | >0.05 | – | – | – |
| Histological subtypes | ||||
| Carcinoid | Reference* | 1 | – | – |
| Adenocarcinoma | 0.003 | 7.68 | 2.0 | 29.43 |
| GIST/leiomyosarcoma | 0.007 5.72 | 1.61 | 20.35 | |
| Year of diagnosis | >0.05 | – | – | – |
| Proposed staging system | ||||
| Stage I (localized) | Reference* | 1 | – | – |
| Stage II (regional) | >0.05 | 2.01 | 0.71 | 5.72 |
| Stage III (metastatic) | 0.04 | 3.84 | 1.04 | 14.22 |
*
Assumed as reference for calculation of hazard ratios.
GIST indicates gastrointestinal stromal tumors; CI, confidence interval; MDC, Meckel diverticulum cancer.