Table 4.
Total and differential cell counts in broncho-alveolar lavage fluid in the severe airway inflammation model.
| Bronchoalveolar cells (*104/ml) (mean ± s.e.m.) | ||||||
|---|---|---|---|---|---|---|
| Groups | Total | Macrophages | Lymphocytes | Neutrophils | Eosinophils | |
| Penh | SAL-SAL | 43.1 ± 8.1 | 42.9 ± 8.1 | 0.03 ± 0.03 | 0 | 0 |
| SAL—TNP-OVA-IgE | 156.8 ± 23.3*** | 125.1 ± 16.8*** | 1.89 ± 0.8 | 29.8 ± 8.4** | 0 | |
| TNP-OVA—SAL | 42.7 ± 4.4 | 42.1 ± 4.4 | 0.27 ± 0.2 | 0.25 ± 0.1 | 0 | |
| TNP-OVA—TNP-OVA-IgE | 552.8 ± 24.7*** | 185.7 ± 9.7*** | 9.63 ± 2.7*** | 2.66 ± 1.6 | 354.8 ± 26.2*** | |
| RL | SAL-SAL | 43.1 ± 6.3 | 42.8 ± 6.3 | 0.09 ± 0.1 | 0.23 ± 0.1 | 0 |
| SAL—TNP-OVA-IgE | 209.8 ± 31.6** | 148.75 ± 21.3** | 4.6 ± 1.8 | 56.5 ± 14.4*** | 0 | |
| TNP-OVA—SAL | 42.2 ± 5.6 | 41.8 ± 5.6 | 0.2 ± 0.1 | 0.1 ± 0.1 | 0 | |
| TNP-OVA—TNP-OVA-IgE | 667.5 ± 56.9*** | 211.9 ± 37.5*** | 26.5 ± 6.2***### | 9.2 ± 5.5 | 419.9 ± 35***# | |
Values are expressed as mean ± s.e.m.
**
P < 0.01,
***
P < 0.001; significantly different from the saline-saline group,
#
P < 0.05;
###
P < 0.001 significant different from the TNP-OVA—TNP-OVA-IgE Penh group, using a One-Way ANOVA followed by a Bonferroni post-hoc analysis.