Table 6.
Chemokine and cytokine concentration in broncho-alveolar lavage fluid in the severe airway inflammation model.
| Penh | RL | |||||||
|---|---|---|---|---|---|---|---|---|
| SAL-SAL | SAL—TNP-OVA-IgE | TNP-OVA—SAL | TNP-OVA—TNP-OVA-IgE | SAL-SAL | SAL—TNP-OVA-IgE | TNP-OVA—SAL | TNP-OVA—TNP-OVA-IgE | |
| IL-10 | n.d. | n.d. | n.d. | n.d. | 7.83 ± 3.06 | n.d. | 16.23 ± 9.86 | 6.12 ± 4.90 |
| IL-12p40 | n.d. | n.d. | n.d. | n.d. | 4.93 ± 2.19 | n.d. | n.d. | 33.87 ± 10.30 |
| IL-1b | n.d. | n.d. | n.d. | n.d. | 5.98 ± 2.94 | n.d. | n.d. | 9.56 ± 5.65 |
| IL-2 | n.d. | n.d. | n.d. | 7.26 ± 2.52 | 2.91 ± 0.71 | 1.28 ± 0.35 | 2.52 ± 0.94 | 6.72 ± 1.42 |
| IL-4 | n.d. | n.d. | n.d. | 5.51 ± 1.86 | n.d. | n.d. | n.d. | 5.14 ± 2.06 |
| IL-5 | n.d. | n.d. | n.d. | 28.67 ± 14.7 | n.d. | n.d. | n.d. | 41.69 ± 26.33 |
| IL-6 | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. |
| IL-9 | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. |
| IP-10 | n.d. | n.d. | n.d. | 42.00 ± 6.08 | n.d. | 101.40 ± 25.48 | n.d. | 11.6 ± 5.61 |
| KC | 85.40 ± 22.11 | 28.24 ± 6.70 | 39.90 ± 2.66 | 169.30 ± 58.66 | 33.1 ± 8.04 | 38.36 ± 7.59 | 14.55 ± 1.19 | 92.89 ± 29.16 |
| MCP-1 | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | 28.29 ± 18.00 |
| MIG | n.d. | n.d. | n.d. | 30.40 ± 4.71 | 5.48 ± 1.82 | 289.20 ± 84.17 | 1.59 ± 0.26 | 11.43 ± 6.10 |
| MIP-1α | n.d. | n.d. | n.d. | 79.70 ± 38.74 | 27.62 ± 17.25 | n.d. | n.d. | n.d. |
| RANTES | 0.91 ± 0.17 | 1.68 ± 0.35 | 0.91 ± 0.21 | 4.70 ± 0.57 | 2.40 ± 0.54 | 0.99 ± 0.36 | 2.73 ± 0.55 | 8.26 ± 0.52 |
| TNFα | 2.23 ± 0.18 | 2.41 ± 0.56 | 2.12 ± 0.01 | 1.62 ± 0.16 | 2.40 ± 0.34 | 1.49 ± 0.23 | 1.74 ± 0.26 | 2.10 ± 0.71 |