Table 1.
Clinical measure | WHO (1998) | IDF (2005) | Joint IDR/NHLBI/AHA |
---|---|---|---|
Insulin resistance | IGT, IFT, T2DM, or lowered insulin sensitivity* Plus any two of the following |
None | None But any three of the following five features |
Body metric | Men: waist-to-hip ratio >0.90 Women: waist-to-hip ratio >0.85 and/or BMI >30kg/m2 |
Increased WC (population specific) plus any two of the following | Population- and country-specific definitions |
Lipid | TG 150 mg/dL and/or HDL-C <35 mg/dL in men or <39 mg/dL in women | TG > 150 mg/dL or on TG Rx | ≥150 mg/dL (1.7 mmol/L) |
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|
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HDL-C <40 mg/dL in men or <50 mg/dL in women or on HDL-C Rx | <40 mg/dL (1.0 mmol/L) in males; <50 mg/dL (1.3 mmol/L) in females | ||
Blood pressure | ≥140/90 mmHg | ≥130 mmHg systolic or 85 mmHg diastolic or on hypertension Rx | Systolic ≥130 and/or diastolic ≥85 mmHg |
Glucose | IGT, IFG, or T2DM | ≥100 mg/dL (includes diabetes) | ≥100 mg/dL |
Other | Microalbuminuria |
MS criteria as defined by WHO, IDF, and the joint IDR/NHLBI/AHA are compared. T2DM indicates type 2 diabetes mellitus; WC, waist circumferences; BMI, body mass index; and TG, triglycerides. All other abbreviations are in text.
Insulin sensitivity measured under hyperinsulinemic euglycemic conditions, glucose uptake below lowest quartile for background population under investigation.