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. Author manuscript; available in PMC: 2014 Aug 12.
Published in final edited form as: Compr Physiol. 2013 Jan;3(1):1–58. doi: 10.1002/cphy.c110062

Table 1.

Established Criteria Proposed for Clinical Diagnosis of Metabolic Syndrome

Clinical measure WHO (1998) IDF (2005) Joint IDR/NHLBI/AHA
Insulin resistance IGT, IFT, T2DM, or lowered insulin sensitivity*
Plus any two of the following
None None
But any three of the following five features
Body metric Men: waist-to-hip ratio >0.90
Women: waist-to-hip ratio >0.85 and/or BMI >30kg/m2
Increased WC (population specific) plus any two of the following Population- and country-specific definitions
Lipid TG 150 mg/dL and/or HDL-C <35 mg/dL in men or <39 mg/dL in women TG > 150 mg/dL or on TG Rx ≥150 mg/dL (1.7 mmol/L)


HDL-C <40 mg/dL in men or <50 mg/dL in women or on HDL-C Rx <40 mg/dL (1.0 mmol/L) in males; <50 mg/dL (1.3 mmol/L) in females
Blood pressure ≥140/90 mmHg ≥130 mmHg systolic or 85 mmHg diastolic or on hypertension Rx Systolic ≥130 and/or diastolic ≥85 mmHg
Glucose IGT, IFG, or T2DM ≥100 mg/dL (includes diabetes) ≥100 mg/dL
Other Microalbuminuria

MS criteria as defined by WHO, IDF, and the joint IDR/NHLBI/AHA are compared. T2DM indicates type 2 diabetes mellitus; WC, waist circumferences; BMI, body mass index; and TG, triglycerides. All other abbreviations are in text.

*

Insulin sensitivity measured under hyperinsulinemic euglycemic conditions, glucose uptake below lowest quartile for background population under investigation.