Table 4.
Association between PAH metabolites and anthropometric measures at birth (adjusted for gestational age and the newborns' gender).
PAH metabolites∗ | Birth weight (g) | Cephalization index (cm/g) | Chest circumference (cm) | Child length (cm) | Head circumference (cm) | Ponderal index (g/cm3) | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
β | SE | P | β | SE | P | β | SE | P | β | SE | P | β | SE | P | β | SE | P | |
1-OH-PHE | −76 | 66 | 0.2 | 1.5 | 1.6 | 0.3 | −0.4 | 0.3 | 0.2 | 0.1 | 0.4 | 0.8 | −0.2 | 0.3 | 0.5 | −0.05 | 0.03 | 0.1 |
2-OH-PHE | −59 | 66 | 0.4 | 1.1 | 1.6 | 0.5 | −0.3 | 0.3 | 0.3 | 0.04 | 0.4 | 0.9 | −0.2 | 0.3 | 0.4 | −0.03 | 0.03 | 0.4 |
3-OH-PHE | −46 | 53 | 0.4 | 1.4 | 1.3 | 0.3 | −0.04 | 0.2 | 0.9 | 0.1 | 0.4 | 0.8 | −0.01 | 0.2 | 1 | −0.03 | 0.03 | 0.3 |
4-OH-PHE | −62 | 57 | 0.3 | 1.9 | 1.4 | 0.2 | −0.2 | 0.2 | 0.4 | −0.2 | 0.4 | 0.5 | −0.1 | 0.2 | 0.6 | −0.02 | 0.03 | 0.5 |
9-OH-PHE | −43 | 47 | 0.4 | 1.5 | 1.1 | 0.2 | −0.1 | 0.2 | 0.6 | 0.1 | 0.3 | 0.8 | 0.1 | 0.2 | 0.7 | −0.02 | 0.02 | 0.4 |
∑OH-PHE | −69 | 66 | 0.3 | 1.5 | 1.6 | 0.3 | −0.3 | 0.3 | 0.3 | 0.1 | 0.4 | 0.8 | −0.1 | 0.3 | 0.6 | −0.04 | 0.03 | 0.2 |
PHE-1,2-diol | 7 | 27 | 0.8 | −0.2 | 0.7 | 0.8 | −0.1 | 0.1 | 0.3 | 0.1 | 0.2 | 0.7 | −0.03 | 0.1 | 0.8 | −0.00 | 0.01 | 0.8 |
PHE-9,10-diol | −19 | 23 | 0.4 | 0.2 | 0.6 | 0.7 | −0.1 | 0.1 | 0.5 | −0.01 | 0.2 | 1 | −0.1 | 0.1 | 0.2 | −0.01 | 0.01 | 0.4 |
∑PHE-diol | −14 | 29 | 0.6 | 0.2 | 0.7 | 0.8 | −0.1 | 0.1 | 0.3 | 0.03 | 0.2 | 0.9 | −0.1 | 0.1 | 0.3 | −0.02 | 0.02 | 0.3 |
1-OH-PYR | −26 | 62 | 0.7 | 0.01 | 1.5 | 1 | −0.3 | 0.3 | 0.2 | −0.2 | 0.4 | 0.6 | −0.3 | 0.2 | 0.3 | −0.01 | 0.03 | 0.7 |
DI-OH-PYR | −13 | 38 | 0.7 | 0.03 | 0.9 | 1 | −0.1 | 0.2 | 0.4 | 0.1 | 0.3 | 0.8 | −0.1 | 0.1 | 0.5 | −0.02 | 0.02 | 0.3 |
∑OH-PYR | −31 | 58 | 0.6 | 0.2 | 1.4 | 0.9 | −0.3 | 0.2 | 0.2 | −0.1 | 0.4 | 0.8 | −0.2 | 0.2 | 0.3 | −0.02 | 0.03 | 0.5 |
β: beta coefficient (and SE standard error).
P:P value.
*PAH metabolites were log-transformed.