Table 6.
Waist circumference and breast cancer risk by body mass index in Nigerian women, 1998–2009
Waist circumference | Cases | Controls | Age-adjusted OR (95% CI) | Adjusted OR (95% CI)† |
---|---|---|---|---|
BMI < 25kg/m2 | ||||
45–81 cm | 412 | 507 | 1.0 (ref.) | 1.0 (ref.) |
82–138 cm | 194 | 96 | 2.03 (1.52–2.71) | 1.91 (1.39–2.61) |
P value | <0.001 | <0.001 | ||
Mean ± SD | 77.6±9.3 | 74.3±7.9 | ||
Per10 cm | 1.31 (1.14–1.51) | 1.26 (1.07–1.47) | ||
| ||||
BMI ≥ 25kg/m2 | ||||
45–81 cm | 65 | 74 | 1.0 (ref.) | 1.0 (ref.) |
82–138 cm | 512 | 419 | 1.15 (0.79–1.68) | 1.11 (0.73–1.68) |
P value | 0.46 | 0.62 | ||
Mean ± SD | 92.9±10.7 | 90.8±9.8 | ||
Per10 cm | 1.13 (1.00–1.27) | 1.08 (0.95–1.23) | ||
| ||||
P for interaction* | 0.021 | 0.042 |
Abbreviations: BMI, body mass index; WHR, waist-hip ratio; OR, odds ratio; CI, confidence interval; SD, standard deviation
Interaction between waist circumference and body mass index
Adjusted for age at diagnosis or interview (categorical), ethnicity, education (categorical), age at menarche (continuous), number of live birth (categorical), age at first live birth (continuous), duration of breastfeeding (categorical), menopausal status, family history of breast cancer, benign breast disease, hormonal contraceptive use, alcohol drinking, and height (continuous).
Categories of waist circumference are based on median in controls.