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. 2014 Aug 9;14:65. doi: 10.1186/1472-6823-14-65

Table 1.

Characteristics of the subjects by sex and BMI categories

 
Men
Women
p gender and BMI interaction
  Lean Overweight Obese p Kruskal Wallis p linearity Lean Overweight Obese p Kruskal Wallis p linearity
N
23
18
10
 
 
14
9
13
 
 
 
Age (years)
33.1 ± 11.4
36.9 ± 9.3
38.3 ± 9.7
0.23
0.15
31.3 ± 12.9
35.3 ± 16.0
34.2 ± 10.7
0.70
0.56
0.91
BMI ( kg/m2)
22.1 ± 1.4
27.7 ± 1.7
35.3 ± 7.4
<0.001
<0.001
23.0 ± 1.4
27.7 ± 1.5
36.3 ± 5.9
<0.001
<0.001
0.86
Percent fat (%)
14.2 ± 3.6
23.2 ± 6.3
33.6 ± 9.6
<0.001
<0.001
26.6 ± 6.0
32.5 ± 8.0
40.8 ± 5.3
<0.001
<0.001
0.28
Waist circumference (cm)
76.0 ± 4.5
92.8 ± 8.4
109.0 ± 12.8
<0.001
<0.001
78.0 ± 6.7
85.4 ± 7.7
102.6 ± 11.4
<0.001
<0.001
0.09
Hip circumference (cm)
87.1 ± 5.9
97.2 ± 6.1
117.1 ± 15.1
<0.001
<0.001
92.0 ± 9.1
106.9 ± 9.7
119.8 ± 13.3
<0.001
<0.001
0.59
Waist-to-hip ratio
0.89 ± 0.03
0.93 ± 0.04
0.92 ± 0.05
0.12
0.10
0.85 ± 0.06
0.80 ± 0.04
0.88 ± 0.08
0.04
0.40
0.04
Waist-to-height ratio
0.44 ± 0.03
0.53 ± 0.05
0.63 ± 0.09
<0.001
<0.001
0.48 ± 0.05
0.52 ± 0.04
0.63 ± 0.07
<0.001
<0.001
0.10
Systolic blood pressure (mmHg)
122 ± 20
131 ± 21
129 ± 10
0.04
0.22
123 ± 22
117 ± 17
125 ± 6
0.29
0.91
0.34
Diastolic blood pressure (mmHg)
72 ± 9
76 ± 11
84 ± 6
0.006
0.002
75 ± 9
71 ± 6
77 ± 5
0.09
0.47
0.11
Total cholesterol (mg/L)
160 ± 43
210 ± 63
275 ± 45
0.002
<0.001
154 ± 61
182 ± 77
235 ± 55
0.02
0.009
0.67
Triglycerides (mg/L)
50 ± 17
57 ± 20
71 ± 47
0.42
0.17
54 ± 14
47 ± 15
71 ± 43
0.22
0.19
0.80
HDL cholesterol (mg/L)
48 ± 18
63 ± 21
70 ± 32
0.37
0.07
47 ± 20
39 ± 11
58 ± 23
0.10
0.22
0.37
LDL cholesterol (mg/L)
102 ± 40
136 ± 54
191 ± 80
0.02
0.006
96 ± 48
133 ± 81
163 ± 64
0.07
0.03
0.82
Fasting glucose (mmol/L)
4.56 ± 0.58
4.42 ± 0.55
4.93 ± 0.56
0.14
0.21
4.46 ± 0.50
4.85 ± 0.70
4.56 ± 043
0.20
0.61
0.04
2 h glucose (mmol/L)
5.46 ± 1.24
5.26 ± 1.00
8.17 ± 3.40
0.002
0.003
6.36 ± 1.21
6.67 ± 1.68
7.02 ± 1.14
0.48
0.25
0.05
Fasting insulin (mU/L)
4.66 ± 2.56
5.71 ± 4.39
8.95 ± 3.60
0.01
0.007
6.72 ± 2.69
9.56 ± 5.94
7.38 ± 3.26
0.44
0.59
0.06
Euglycaemic clamp
 
 
 
 
 
 
 
 
 
 
 
M unadjusted (mg.min−1.kg−1)
10.0 ± 2.7
7.5 ± 2.4
5.2 ± 1.8
<0.001
<0.001
8.4 ± 2.2
7.6 ± 2.8
6.1 ± 1.7
0.02
0.01
0.13
M adjusted to lean mass (mg.min−1.kg−1)
11.6 ± 2.9
9.8 ± 3.3
7.8 ± 2.9
0.004
0.001
11.5 ± 2.7
11.1 ± 3.4
10.4 ± 3.1
0.70
0.35
0.27
Fasting indices
 
 
 
 
 
 
 
 
 
 
 
Plasma insulin (mUI/mL)
4.7 ± 2.6
5.7 ± 4.4
8.9 ± 3.6
0.01
0.007
6.7 ± 2.7
9.6 ± 5.9
7.4 ± 3.3
0.44
0.59
0.06
Glucose/Insulin ratio (mmol/mUI)
25.5 ± 18.7
21.6 ± 13.3
11.6 ± 4.9
0.03
0.07
15.7 ± 12.0
13.6 ± 12.1
14.0 ± 6.8
0.50
0.69
0.30
HOMA-IR
0.95 ± 0.57
1.11 ± 0.89
2.00 ± 0.93
0.009
0.004
1.33 ± 0.56
2.08 ± 1.32
1.53 ± 0.65
0.34
0.47
0.02
FIRI
0.85 ± 0.51
1.01 ± 0.80
1.80 ± 0.84
0.009
0.004
1.20 ± 0.50
1.88 ± 1.19
1.37 ± 0.58
0.34
0.47
0.02
QUICKI 0.30 ± 0.15 0.19 ± 0.10 0.11 ± 0.03 0.01 0.10 0.15 ± 0.08 0.13 ± 0.08 0.13 ± 0.03 0.37 0.46 0.32

BMI: body mass index; HDL: high density lipoprotein cholesterol; LDL: low density lipoprotein cholesterol; HOMA-IR: Homeostasis Model Assessment for insulin resistance; FIRI: fasting insulin resistance index; QUICKI: quantitative insulin sensitivity check index.