Table 3.

Proportion of subjects correctly classified by each index using clamp-derived M thirds as reference insulin sensitivity categories

	Men					Women					All subjects
Insulin sensitivity category	Low	Medium	High	Total	Kappa (95% CI)	Low	Medium	High	Total	Kappa (95% CI)	Low	Medium	High	Total	Kappa (95% CI)
Using clamp as reference	N = 15	N = 16	N = 16	N = 47		N = 10	N = 11	N = 11	N = 32		N = 25	N = 27	N = 27	N = 79
Fasting plasma insulin	20%	44%	25%	14/47	−0.05 (−0.25 to 0.14)	30%	36%	9%	8/32	−0.13 (−0.33 to 0.10)	24%	41%	18%	22/79	−0.08 (−0.22 to 0.08)
Glucose/Insulin ratio	53%	56%	50%	25/47	0.30 (0.08 to 0.51)	50%	45%	45%	15/32	0.20 (−0.08 to 0.47)	52%	52%	48%	40/79	0.26 (0.09 to 0.42)
HOMA-IR	20%	37%	19%	12/47	−0.12 (−0.30 to 0.06)	20%	45%	18%	9/32	−0.08 (−0.31 to 0.15)	20%	41%	18%	21/79	−0.10 (−0.24 to 0.04)
FIRI	20%	37%	19%	12/47	−0.12 (−0.30 to 0.08)	20%	45%	18%	9/32	−0.08 (−0.30 to 0.16)	20%	41%	18%	21/79	−0.10 (−0.24 to 0.04)
QUICKI	53%	50%	50%	24/47	0.27 (0.05 to 0.46)	50%	36%	54%	15/32	0.20 (−0.04 to 0.47)	52%	44%	52%	39/79	0.24 (0.09 to 0.42)
Age	27%	9%	56%	15/47	−0.02 (−0.22 to 0.18)	10%	45%	27%	9/32	−0.08 (−0.32 to 0.16)	20%	26%	44%	24/79	−0.04 (−0.19 to 0.11)
BMI	53%	56%	62%	27/47	0.36 (0.14 to 0.58)	50%	27%	27%	11/32	0.01 (−0.23 to 0.25)	52%	44%	48%	38/79	0.22 (0.05 to 0.38)
Waist	53%	31%	56%	21/47	0.20 (−0.02 to 0.40)	50%	27%	18%	10/32	−0.03 (−0.26 to 0.22)	52%	30%	41%	32/79	0.11 (−0.06 to 0.27)
WHtR	53%	31%	62%	25/47	0.23 (0.01 to 0.43)	50%	36%	18%	11/32	0.01 (−0.22 to 0.25)	52%	33%	44%	34/79	0.14 (−0.02 to 0.31)

HOMA-IR: Homeostasis Model Assessment for insulin resistance; FIRI: fasting insulin resistance index; QUICKI: quantitative insulin sensitivity check index;

BMI: body mass index; WHtR: waist-to-height ratio.