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Osteoblast differentiation and proliferation at reversal sites. (a) Gradients of markers between canopy cells and reversal cells. Ki67: proliferation marker; P3NP: early differentiation marker. Data from ref. 22. (b and c) Gradients of markers between early (that is, next to the osteoclasts) and late (that is, next to osteoblasts depositing osteoid) reversal cells, and between active and arrested reversal cells. See text. Data from ref. 11.
