Figure 3.

Mean total distances traveled over 3-minute intervals (by the methods illustrated in Fig. 2) by melanosomes (black bars, n = 65) and lipofuscin granules (white bars, n = 56) within the same RPE cells. Data for distance traveled during and after light treatment are expressed as a percent of baseline motility (± SD). Reductions in movement relative to baseline are significantly greater for lipofuscin granules than for melanosomes during light treatment and after irradiation (P < 0.05, t-test). Age of RPE donor: 62 years.