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. Author manuscript; available in PMC: 2014 Aug 12.
Published in final edited form as: Nutr Rev. 2012 Aug 17;70(9):491–508. doi: 10.1111/j.1753-4887.2012.00508.x

Table 4.

Summary of significant (multivariate adjusted ptrend<.05) associations between flavonoid intakes and various cardiovascular outcomes in prospective cohorts in US and European countries

Number of cohorts with significant associations/number of cohorts examined

Mortality Incidence Number
cohorts
All
publications
Flavonoid Class CHD Stroke CVD CHD Stroke CVD
Flavonols & flavones 1a/6e 0/1 0/1 0/6e 1/4 0/1 1/8 3/11
Flavonols 2/5d 0/1 0/2 0/5 2/3c 0/1 3/9 3/10
Flavones 0/1a 0/1 0/2 1/1 0/2 0/1 1/4 1/5
Flavanones 1/2 0/1 1/2 1/2 2/3 2/3
Flavan-3-ols 1/2b 0/2 0/2 0/1 0/2 1/3 1/4
Anthocyanidins 1/1 0/1 1/2 0/1 1/2 1/2
Isoflavones 0/1 0/1 0/1 0/1 0/1 0/1 0/2 0/2
Proanthocyanidins 0/1 0/1 0/1 0/1 0/1
Number of cohorts studied 4/8 0/2 1/3 1/9 3/7 0/2 6/12
All publications 6/13 0/3 1/3 1/11 3/9 0/2 8/20
a

two publications

b

three publications

c

four publications

d

six publications

e

seven publications