Table 1. Dose-escalating immunogenicity of H₂ vaccine in single dose among children aged 6 to 8 y, 3 mo after vaccination^@.

Group	Dose (TCID50)	n	Anti-HAV# Rate		Anti-HAV GMT (mIU/mL) (95% CI^)
			(+)	% (95% CI^)
A	106.17	38	32	84.2 (72.6–95.8)	46.3	34.7–61.9
B	106.52	47	43	91.5 (83.5–99.5)	75.0	53.5–105.3
C	106.83	46	44	95.7 (89.7–100)	197.9	141.8–276.3
D*	106.83	23	17	73.9 (55.9–91.8)	41.3	26.6–64.1

⁺ This table was adopted with permission from Wang XY, et al. Immunogenicity and long-term persistence of anti-HAV induced by the live attenuated or inactivated hepatitis A vaccine. Zhong Hua Liu Xing Bing Xue Za Zhi 2001; 22:111–3. *Group D vaccine was inactivated at 60 °C for 3 h. ^95% Confidence Interval. ^#anti-HAV IgG. @ Dose-response for Group A, B, and C: Cochran–Armitage test statistic = 2.78, P < 0.01 ; comparison of anti-HAV positivity between Group C and D: χ² = 5.10, P < 0.05.