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. 2013 Dec 10;10(3):724–733. doi: 10.4161/hv.27340

Table 1. Immunization regimen and the frequency of SIV antigen specific IFN-γ spot-forming cells.

Group Immunization Dosagea Spot-forming cells for structural antigens Spot-forming cells for non-structural antigens
1 rAd5-empty 1.0 × 1010 vp 53 ± 24 21 ± 5
2 rAd5-SIV 0.5 × 1010 vp 342 ± 38 2 ± 1
3 rAd5-SIV + 0.5 × 1010 vp 1068 ± 72 25 ± 4
  rAd5-sPD1 0.25 × 1010 vp    
4 rAd5-SIV + 0.5 × 1010 vp 564 ± 31 5 ± 2
  rAd5-sTim3 0.25 × 1010 vp    
5 rAd5-SIV + 0.5 × 1010 vp 1801 ± 64 175 ± 18
  rAd5-sPD1 +
rAd5-sTim3		 0.25 × 1010 vp
0.25 × 1010 vp		    

a rAd5 vectors at 1 × 1010 viral particles (vp) final dose were used to immunized mice. rAd5-empty was used to make up the final dose (0.5 × 1010 vp for group 2 and 0.25 × 1010 vp for groups 3 and 4).