Table 2. The crude and adjusted IVE estimates of the 2012–2013 seasonal vaccine of GrippeNet.fr participants reporting an ILI defined by the presence of fever ≥38 °C and cough (significant results appear in bold).
| Crude OR (95% CI) | Adjusted OR (95% CI) | Corrected OR (95% CI) | P value (multivariate analysis, analysis of deviance) | |
|---|---|---|---|---|
| Vaccination | ||||
| Influenza vaccination during the current season | 0.38 (0.24 to 0.60) | 0.49 (0.31 to 0.79) | 0.51 (0.33 to 0.80) | <10−3 |
| Socio-demographic factors | ||||
| Gender (women) | 0.99 (0.67 to 1.46) | 1.09 (0.74 to 1.61) | 1.07 (0.77 to 1.47) | 0.51 |
| Age: | ||||
| 0–49 | 1 | 1 | 1 | 0.045 |
| 50–64 | 0.36 (0.25 to 0.52) | 0.60 (0.39 to 0.92) | 0.62 (0.41 to 0.93) | |
| ≥65 | 0.34 (0.22 to 0.53) | 0.77 (0.45 to 1.32) | 0.78 (0.47 to 1.29) | |
| Presence of a child (under five years) in the household | 3.43 (2.23 to 5.30) | 2.24 (1.39 to 3.61) | 1.61 (1.24 to 1.97) | <10−3 |
| Health factors | ||||
| To take regular medication for asthma | 1.66 (0.76 to 3.63) | 1.69 (0.71 to 4.02) | 1.46 (0.76 to 2.36) | 0.051* |
| To take regular medication for a lung disorder | 0.59 (0.17 to 2.01) | 0.60 (0.12 to 3.10) | 0.63 (0.13 to 2.56) | 0.41 |
| To take regular medication for diabetes, a heart disorder, kidney disorder or an immunocompromising condition | 0.67 (0.37 to 1.21) | 1.30 (0.72 to 2.36) | 1.26 (0.74 to 2.04) | 0.32 |
| Frequency of cold/flu: | ||||
| - Less than one per year | 1 | 1 | 1 | <10−3 |
| - One or two per year | 1.78 (1.13 to 2.80) | 1.49 (0.93 to 2.38) | 1.39 (0.94 to 1.98) | |
| - At least three per year | 4.17 (2.56 to 6.78) | 2.75 (1.63 to 4.63) | 1.83 (1.38 to 2.28) | |
*P value of the Wald test = 0.24