Table 3. Seroconversion rates of influenza antibody after immunization in the study groups.
Age group | Subgroup | No. of subjects | Antibody seroconversion (H1N1) | Antibody seroconversion (H3N2) | Antibody seroconversion (B) | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
No. | Percentage | P value | No. | Percentage | P value | No. | Percentage | P value | |||
3–10 y | T1 | 149 | 128 | 85.9 | 140 | 94 | 136 | 91.3 | |||
T2 | 146 | 123 | 83.7 | <0.001* | 140 | 95.2 | <0.001* | 132 | 89.8 | <0.001* | |
T3 | 140 | 126 | 90 | 0.285† | 133 | 95 | 0.870† | 129 | 92.1 | 0.779† | |
C | 218 | 36 | 16.4 | 31 | 14.2 | 80 | 36.5 | ||||
11–17 y | T1 | 166 | 161 | 97 | 164 | 98.8 | 125 | 75.3 | |||
T2 | 166 | 152 | 91.6 | <0.001* | 161 | 97 | <0.001* | 135 | 81.3 | <0.001* | |
T3 | 159 | 147 | 91.9 | 0.081† | 157 | 98.1 | 0.499† | 130 | 81.3 | 0.301† | |
C | 251 | 14 | 5.6 | 6 | 2.4 | 11 | 4.4 | ||||
18–54 y | T1 | 155 | 139 | 89.1 | 115 | 73.7 | 95 | 60.9 | |||
T2 | 156 | 136 | 87.2 | <0.001* | 121 | 77.6 | <0.001* | 95 | 60.9 | <0.001* | |
T3 | 151 | 134 | 88.7 | 0.854† | 117 | 77.5 | 0.661† | 101 | 66.9 | 0.458† | |
C | 229 | 35 | 15.2 | 14 | 6.1 | 46 | 20 | ||||
≥55 y | T1 | 152 | 127 | 83 | 145 | 94.8 | 116 | 75.8 | |||
T2 | 150 | 130 | 86.7 | <0.001* | 145 | 96.7 | <0.001* | 122 | 81.3 | <0.001* | |
T3 | 162 | 141 | 87 | 0.537† | 156 | 96.3 | 0.675† | 127 | 78.4 | 0.505† | |
C | 234 | 18 | 7.7 | 18 | 7.7 | 14 | 6 |
Seroconversion rate, the proportion of subjects whose antibody GMT met the definition of seroconversion after vaccination; H1N1, H3N2, B, three strains of influenza; *P value between experimental and control groups; †P value between three experimental groups (three batches of influenza vaccine).