Table 1.
Genes Identified through ts Mutants that Affect rRNA Processing
| ORF Name | Gene Name(s) | Description | rRNA Defect | Percent Reduction |
|---|---|---|---|---|
| YAL043C | PTA1, FUN39 | Subunit of holo-CPF, mRNA, snoRNA pre-tRNA processing; binds phospho-CTD of RNAPII | 18Sa | 22.4 |
| YDR196C | Coenzyme A biosynthesis; mitochondrial | 18S | 11.3 | |
| YDR339C | FCF1, UTP24 | SSU processome component | 18S | 11 |
| YGR145W | ENP2 | Nucleolar | 18S | 23.5 |
| YGR277C | Coenzyme A biosynthesis | Not significant | ||
| YJL069C | UTP18 | Possible U3 snoRNP protein | 25S | 5.9 |
| YKL033W | FMP47 | Mitochondrial | 18S | 16.9 |
| YKR022C | NTR2 | Spliceosome disassembly | 18S | 9 |
| YLR132C | Mitochondria and nucleus | Not significant | ||
| YOL022C | Cytoplasmic | 18S | 9.1 | |
| YOR004W | UTP23 | SSU processome component | 18S | 8.1 |