Table 1. Referral and Final Pathologic Diagnoses for Patients with T-cell Lymphoma (n = 131).
NCCN Diagnosis | |||||
---|---|---|---|---|---|
Referral Diagnosis | PTCL NOS | AITL | ALK+ ALCL | ALK-ALCL | Total |
PTCL NOS | 15 | 4 | 0 | 3 | 22 |
AITL | 0 | 11 | 0 | 0 | 11 |
ALK+ ALCL | 0 | 0 | 13 | 0 | 13 |
ALK- ALCL | 1 | 0 | 0 | 18 | 19 |
ALCL, no ALK status | 0 | 0 | 0 | 2 | 2 |
Anaplastic T-cell/NK-cell lymphoproliferative neoplasm | 0 | 0 | 0 | 1 | 1 |
DLBCL | 1 | 1 | 0 | 0 | 2 |
EMZL | 0 | 1 | 0 | 0 | 1 |
Classical Hodgkin lymphoma | 1 | 1 | 0 | 3 | 5 |
EATL | 1 | 0 | 0 | 0 | 1 |
T-cell lymphoma without WHO designation | 4 | 1 | 0 | 1 | 6 |
Atypical lymphoid proliferation | 1 | 1 | 0 | 0 | 2 |
Benign/Reactive | 0 | 2 | 1 | 0 | 3 |
No definitive diagnosis rendered | 0 | 0 | 0 | 1 | 1 |
Final diagnosis | 24 | 22 | 14 | 29 | 89 |
Provisional diagnosis | 24 | 11 | 4 | 3 | 42 |
Total cases evaluated | 48 | 33 | 18 | 32 | 131 |
Discordant cases | 9 (19%) | 11 (33%) | 1 (6%) | 11 (34%) | 32 (24%) |
PTCL NOS indicates peripheral T-cell lymphoma, not otherwise specified, AITL indicates angioimmunoblastic T-cell lymphoma, ALK+ ALCL indicates ALK-positive anaplastic large cell lymphoma, ALK-ALCL indicates ALK-negative anaplastic large cell lymphoma, DLBCL indicates diffuse large B-cell lymphoma, EMZL indicates extranodal marginal zone lymphoma, EATL indicates enteropathy-associated T-cell lymphoma, TCL indicates T-cell lymphoma