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. 2014 Aug 12;9(8):e103059. doi: 10.1371/journal.pone.0103059

Table 2. Cytokine levels correlate with cell type in preterm lavage.

IL-1β CXCL8 CCL3 CCL4 IL-10
Cell type p r2 p r2 p r2 p r2 p r2
CD15+ - - - - - - 0.04 0.42 0.02 0.54
CD14/16+ - - - - - - 0.04 0.47 - -
CD14/36+ - - - - - - 0.03 0.44 - -
CD14/HLA-DR+ 0.001 0.69 0.003 0.63 - - 0.0004 0.77 0.0001 0.89

Preterm infants were ventilated and lavaged within 24 hours of birth and cells stained with combinations of anti-CD15, anti-CD14, anti-CD16, anti-HLA-DR, anti-CD36 or matched isotype antibodies and analysed by flow cytometry. Cytokine bead arrays were carried out on cell-free lavage and the following cytokines were measured: IL-1β, CXCL8, CCL3, CCL4, and IL-10. Correlations of cytokine levels and absolute numbers of cells were analysed by linear regression and significant correlations are shown in the table.