Table 2. Baseline characteristics of patients from coronary segment subcohort with coronary artery disease, stratified for the presence of a CTO observed on angiography.
| CTO observed (n = 14,609) | Missing % | CTO not observed (n = 76,545) | Missing % | P-value | |
| Male gender (%) | 77.7 | 0 | 70.6 | 0.0 | <0.01 |
| Age (median, IQR) | 68 (61–76) | 0.2 | 68 (60–75) | 0.2 | <0.01 |
| Diabetes (%) | 24.0 | 1.0 | 18.6 | 0.8 | <0.01 |
| Hypertension (%) | 62.0 | 2.4 | 52.5 | 2.0 | <0.01 |
| Hyperlipidemia (%) | 61.9 | 2.8 | 44.4 | 2.5 | <0.01 |
| Smoking status (%) | 5.8 | 5.5 | <0.01 | ||
| Current smoker | 20.0 | 21.6 | |||
| Previous smoker | 40.0 | 35.0 | |||
| Previous MI (%) | 37.0 | 3.8 | 16.5 | 2.3 | <0.01 |
| Previous PCI (%) | 17.5 | 0.1 | 10.7 | 0.05 | <0.01 |
| Cardiogenic shock(%)* | 10.1 | 1.0 | 3.5 | 1.3 | <0.01 |
| Creatinine Clearance | 80 | 28.2 | 81 | 34.2 | <0.01 |
| (ml/min) | (60–103) | (62–103) | |||
| CCS class (%)** | 6.9 | 5.5 | 0.19 | ||
| I | 9.3 | 9.6 | |||
| II | 53.4 | 54.7 | |||
| III | 36.0 | 34.5 | |||
| IV | 1.3 | 1.2 | |||
| Indication (%) | 0 | 0 | <0.01 | ||
| Stable CAD | 44.5 | 17.1 | |||
| Unstable CAD/NSTEMI | 26.3 | 49.6 | |||
| STEMI | 15.1 | 26.0 | |||
| Other | 14.0 | 7.3 | |||
| Extent of CAD (%) | 1.5 | 1.2 | <0.01 | ||
| 1 vessel | 17.4 | 48.7 | |||
| 2 vessel | 35.1 | 25.9 | |||
| 3 vessel | 38.3 | 17.2 | |||
| Left main disease*** | 9.2 | 8.2 |
CAD: coronary artery disease, CCS: Canadian cardiovascular society, CTO: chronic total occlusion, IQR: inter quartile range, MI: myocardial infarction, (N)STEMI: (non-)ST-elevation myocardial infarction, PCI: percutaneous coronary intervention.
* Cardiogenic shock only displayed for the indication STEMI.
**CCS class only displayed for the indication stable CAD.
*** Left main (LM) disease includes: LM+1 vessel, LM+2 vessel and LM+3 vessel.