Table 3. Baseline characteristics of CTO patients from coronary segment subcohort according to the treatment strategy.

	No PCI of CTO (n = 8,182)		PCI of CTO (n = 3,251)		Referral for CABG (n = 3,172)
	(%)	Missing (%)	(%)	Missing (%)	(%)	Missing (%)	P-value
Male gender	76.2	0	76.5	0	82.9	0	<0.01
Age (median, IQR)	69 (61–77)	0.2	66 (59–74)	0.2	68 (61–74)	0.2	<0.01
Diabetes	24.0	1.1	21.0	1.2	26.9	0.4	<0.01
Hypertension	61.6	3.0	59.8	2.3	65.2	1.5	<0.01
Hyperlipidemia	58.6	3.4	60.2	2.7	71.2	1.3	<0.01
Smoking status		7.0		5.0		3.6	<0.01
Current smoker	21.4		20.7		15.5
Previous smoker	39.4		39.5		42.1
Previous MI	41.3	4.1	33.4	3.5	29.4	3.2	<0.01
Previous PCI	19.9	0.1	20.3	0.2	8.3	0.03	<0.01
Cardiogenic Shock **	10.0	1.0	10.4	0.9	0	0	0.84
Creatinine Clearance (ml/min)	77 (57–101)	31.6	85 (65–109)	26.1	82 (64–102)	21.8	<0.01
CCS class *		7.1		4.6		7.8	<0.01
I	13.2		8.6		5.3
II	55.2		56.3		49.8
III	30.3		34.3		43.3
IV	1.4		0.8		1.6
Indication		0		0		0	<0.01
Stable CAD	33.1		41.3		77.4
Unstable CAD/NSTEMI CAD/NSTEMI	31.1		39.8		0.4
STEMI	21.7		13.5		0
Other	14.2		5.5		22.2
Extent of CAD (%)		1.2		1.3		1.3	<0.01
1 vessel	14.9		36.5		4.2
2 vessel	40.9		39.6		15.8
3 vessel	37.9		21.1		56.8
Left main disease***	6.3		2.8		23.2

CAD: coronary artery disease, CCS: Canadian cardiovascular society, CTO: chronic total occlusion, IQR: inter quartile range, MI: myocardial infarction, (N)STEMI: (non-)ST-elevation myocardial infarction, PCI: percutaneous coronary intervention.

* Cardiogenic shock only displayed for the indication STEMI.

**CCS class only displayed for the indication stable CAD.

*** Left main (LM) disease includes: LM+1 vessel, LM+2 vessel and LM+3 vessel.

Data about initial treatment strategy were missing in four CTO patients.