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. Author manuscript; available in PMC: 2014 Aug 12.
Published in final edited form as: Hepatology. 2009 Dec;50(6):1893–1903. doi: 10.1002/hep.23238

Figure 4.

Figure 4

Immunological profiles of liver MNC in anti-CD20-mAb- and control-mAb-treated dnTGF-βRII mice.

Absolute numbers of CD19+ B, CD4+ T, CD8+ T, CD44hiCD4+ T, and CD44hiCD8+ T cells were demonstrated for gram of liver and spleen. Depletion of CD19+ B cells was accomplished in both liver and spleen by anti-CD20 treatment in younger and older groups. Absolute number of liver CD8+ T cells and their activated phenotypes were significantly decreased in livers of anti-CD20 treated younger dnTGF-βRII mice (n = 6) compared to that of control-mAb-treated mice (n = 8) whereas those difference was not obvious in older mice after anti-CD20 treatment. (*p < 0.05, **p < 0.01, ***p < 0.001 in Mann-Whitney Test)