. 2014 Aug 12;9(8):e104791. doi: 10.1371/journal.pone.0104791

Table 4. Peste des petitsruminants virus (PPRV) neutralizing antibody titers and lymphocyte proliferation responses in goats immunized with PPRV virus-like particles (VLPs) or native PPRV particles.

Group	Neutralization titer (Weeks post primary immunization)								Mean stimulation Index^*
	0	1	2	3	5	7	11	15
PPRV-H VLP	<5	5–10	20–40	40–80	80–160	80–160	160	80–160	2.44±0.20^a
PPRV-F VLP	<5	<5	5–10	5–20	10–80	40–160	40–80	40–80	2.32±0.18^a
PPRV	<5	5–10	20–80	40–80	80–160	160–320	160–320	160–320	2.61±0.32^a
PBS	<5	<5	<5	<5	<5	<5	<5	<5	1.21±0.10^b

PPRV neutralizing antibody titers in goats immunized with the PPRV VLPs, PPRV, and PBS. Serum samples were collected at weeks 0,1,2, 3, 5, 7, 11, and 15 after primary vaccination. Proliferation responses of peripheral blood lymphocytes in goats were tested at week 2 after boost immunization.

PBS = phosphate-buffered saline, as negative control; PPRV = Peste des petits virus; VLP = virus-like particles.

*Different superscript letters indicate that the differences were significant (p<0.05), same superscript letters indicate that the differences were not significant (p>0.05). (according to one-way ANOVA, using GraphPad).