Skip to main content
. 2014 Aug 12;9(8):e104897. doi: 10.1371/journal.pone.0104897

Table 1. Main characteristics of the 83 study patients at ICU admission.

Median [IQR] or N (%)
Demographics
Age in years 61.7 [48.4–74.5]
Male 56 (67.5%)
Current smoker 64 (77%)
Known cardiovascular disease 43 (51.8%)
Poor chronic health status (Performance status ≥2) 31 (32.4%)
Exposure to pneumotoxic drugs 30 (36.1%)
Clinical presentation
Days from respiratory symptom onset to ICU admission 11 [5][28]
Crackles at chest auscultation 76 (91.6%)
Shock 42 (50.6%)
Acute kidney injury 42 (50.6%)
Significant proteinuria 33 (45.2%)
Skin rash 25 (30.1%)
Arthralgia 11 (13.3%)
ILD subgroups
Toxic 22 (26.5%)
Drug-induced ILD/Pneumoconiosis 14/3
Radiation pneumonitis/Hypersensitivity pneumonitis 2/3
Connective tissue diseases 28 (33.7%)
Rheumatoid arthritis 5/28
Scleroderma 6/28
Polymyositis/dermatomyositis 2/28
Primary Sjogren’s syndrome 3/28
Mixed connective tissue disease 5/28
Antisynthetase syndrome 2/28
Systemic lupus erythematosus/antiphospholipid syndrome 2/28
Miscellaneous 3/28
Idiopathic interstitial pneumonia (acute ILD) 19 (22.8%)
Cryptogenic organising pneumonia 7
Acute interstitial pneumonia 8
Lymphocytic interstitial pneumonia 2
Idiopathic acute eosinophilic pneumonia 2
Acute exacerbation of chronic idiopathic ILD 17 (20.5%)
Idiopathic pulmonary fibrosis (IPF) 9
Chronic idiopathic interstitial lung disease (other than IPF) 8
Langerhans cell histiocytosis 2 (2.4%)

Abbreviations: RV, right ventricular; ILD, interstitial lung disease.