Skip to main content
. 2014 Aug 12;9(8):e104897. doi: 10.1371/journal.pone.0104897

Table 2. Severity, ICU management and outcomes.

Median [IQR] or N (%)
SOFA score at ICU admission 5 [3.5–8]
Criteria for Acute respiratory distress syndrome * 60 (73.2%)
Mild/Moderate/Severe 4 (6.6%)/9 (15%)/47 (78.3%)
Pulmonary hypertension (RV dysfunction) Inline graphic 32 (40.5%)
Ventilatory support
High flow oxygen 77 (92.8%)
Non-invasive ventilation alone 12 (14.5%)
Non-invasive ventilation followed by intubation 17 (20.5%)
First line invasive mechanical ventilation 33 (39.8%)
Treatments
Antibiotics 78 (95.1%)
High-dose steroids
No 29 (34.9%)
Yes, but with no respiratory response¥ 22/54 (40.7%)
Yes, with respiratory response¥ 32/54 (59.3%)
Other immunosuppressive drugs£ 14 (16.9%)
Outcomes
ICU length of stay 8 [3], [14]
Hospital length of stay 20 [11, 35]
Hospital mortality 34 (41%)
6-month mortality 43 (52.4%)
1-year mortality 44 (53.7%)
Treatment-limitation decisions 22 (26.5%)

*ARDS was defined using Berlin criteria [2].

Inline graphicPulmonary hypertension (right ventricular dysfunction) was assessed by transthoracic echocardiography (excluding left ventricular dysfunction).

¥ Responsiveness to corticosteroids was defined as an increase in the ratio of arterial oxygen saturation (PaO2) over fraction of inspired oxygen (FiO2) ratio to more than 100 mmHg within 1 week of initiating high-dose corticosteroid therapy.

£ cyclophophamide or rituximab.