Skip to main content
. 2014 Aug 12;9(8):e104897. doi: 10.1371/journal.pone.0104897

Table 3. Diagnostic investigations.

Median [IQR] or N (%)
Chest-X-Ray 83 (100%)
Interstitial infiltration 83 (100%)
Alveolar opacities 42 (50.6%)
Pleural effusion 17 (20.5%)
Chest CT (n = 67, 80.7%) *
Ground-glass opacities 47 (70.1%)
Diffuse 43/47 (91.5%)
Focal 4/47 (8.5%)
Fibrosis (traction bronchiectasis and/or honeycombing) 24 (35.8%)
Diffuse 11/24 (45.8%)
Focal 13/24 (54.2%)
Air-space consolidations 22 (32.8%)
Interlobular septal thickening 20 (29.9%)
Cysts 3 (4.5%)
Pleural effusions 20 (29.9%)
Pneumothorax 0 (0%)
Bronchoalveolar lavage (n = 53, 63.9%) Inline graphic
Cell count/µL 480 [170.5–1080]
Lymphocytes >15% of total cells 20 (38.5%)
Neutrophils >10% of total cells 29 (55.8%)
Eosinophils >1% of total cells 4 (7.7%)
Diffuse intra-alveolar haemorrhage (>20% siderophages) 11 (21.2%)
Positive bacterial culture of sputa or BAL 10 (12.5%)
Virus identified by PCR in BAL or nasopharyngeal aspirates 9 (12.7%)
Lung biopsy 11 (13%)
Positive auto-immune antibodies 27 (32.5%)

*In 16 instances, CT scan was not performed because of severe hypoxemia precluding transportation to the radiological department.

Inline graphicIn 30 instances, results for BAL were not available either because BAL was not performed due to severe hypoxemia or the BAL results were deemed uninterpretable.