Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Aug 12;9(8):e105131. doi: 10.1371/journal.pone.0105131

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Xu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(a) Dose-effects of celastrol on NB4 numbers. NB4 cells were treated with different doses of celastrol for 1 or 3 d, then the cellular number determined by one-tube platform flow cytometry (detailed in Material and Methods). (b) The effects of celastrol on cell cycle distribution in NB4. The cells were treated with celastrol at 200 nM or DMSO for 3d, and then the cell cycles were analyzed with flow cytometry. (c) Time-effects of celastrol on cellular number in NB4 co-treated with ATRA. NB4 cells were pre-treated with celastrol at 200 nM (or not) for 30 min, before 1 µM of ATRA was loaded (or not). The cellular numbers at the different indicated time points were determined by one-tube platform flow cytometry. In panels A and B, the data are shown as mean ± SE. * represents P<0.05, while ** and *** represent P<0.01 and P<0.001, respectively, with a sample size (n) of 3.