Figure 3. Chronic exposure to AS promotes tumor growth in NOD/SCID mice. (A and B) HT-29 cells were exposed to 0 or 15 nM AS for 0, 30, or 60 passages. Representative images of animals (A) with subcutaneous implanted tumor, and (B) isolated tumors taken on day 40. (C) The subcutaneous tumor growth curves. (D) Quantification of the tumor weight. *P < 0.05; **P < 0.01.