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. Author manuscript; available in PMC: 2014 Aug 12.
Published in final edited form as: Neuroimage. 2012 Aug 21;63(4):1854–1863. doi: 10.1016/j.neuroimage.2012.08.028

Fig. 1.

Fig. 1

Drug and group effects on relative glucose metabolism. Upper panel depicts p<0.005 statistical interactions in the regions of interest (ROIs – outlined in green) between group and drug effects (compared to placebo), superimposed on a structural MRI representing atlas space. Lower panel depicts individual group effects responsible for the interaction above. Other possible interactions and contributing group effects were insignificant. Yohimbine effects are depicted on slices 6 mm to the left, 2 mm anterior, and 14 mm inferior to the anterior commissure (i.e., MNI coordinates −6, 2, −14). Clonidine effects are depicted at MNI −4, 24, −8. All figures depict neurological orientation (left=left). sgACC = subgenual cingulate, pgACC = pregenual cingulate, MCC = mid cingulate cortex, aINS = anterior insula, pINS = posterior insula, amyg = amygdala, DBS = dorsal brainstem, and vlPFC = ventrolateral prefrontal cortex.