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Immunohistochemical detection of interleukin-1β. Representative micrographs showing interleukin (IL)-1β immunoreactivity in hematoxylin counterstained kidney sections from animals with severe acute pancreatitis (SAP) (magnification × 200). Saline treatment A: 6 h; C: 12 h; and E: 18 h after SAP induction. Caspase-1 inhibitor treatment B: 6 h; D: 12 h; and F: 18 h after SAP induction.
