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Antigens used for expression in OMVs
| Antigen | Pathogen | Functional assay | Protective immune responses |
|---|---|---|---|
| SpyCEP | S. pyogenes | IL-8 cleavage | Neutralizing Ab and mouse challenge |
| Streptolysin O | S. pyogenes | Haemolysis | Neutralizing Ab and mouse challenge |
| Spy0269 | S. pyogenes | Not available | Mouse challenge |
| SAM_1372 | S. agalactiae | Not available | Opsonophagocytic activity |
| R-TEM b-lac | E. coli | Hydrolysis of Nitrocefin | Not available |
