Table II.
Antigen | Pathogen | Functional assay | Protective immune responses |
---|---|---|---|
SpyCEP | S. pyogenes | IL-8 cleavage | Neutralizing Ab and mouse challenge |
Streptolysin O | S. pyogenes | Haemolysis | Neutralizing Ab and mouse challenge |
Spy0269 | S. pyogenes | Not available | Mouse challenge |
SAM_1372 | S. agalactiae | Not available | Opsonophagocytic activity |
R-TEM b-lac | E. coli | Hydrolysis of Nitrocefin | Not available |