Figure 7.

SCI did not change microglial phenotypes in the hippocampus and cerebral cortex at 8 d after injury. A, Representative Iba-1 IHC images displaying resting (ramified morphology) or activated (hypertrophic or bushy morphology) microglial phenotypes and the corresponding Neurolucida reconstructions. B, C, Unbiased stereological quantitative assessment in the hippocampus (B) and cerebral cortex (C) revealed no differences in the numbers of resting, activated, and total microglia between SCI and uninjured mice. n = 4 (Sham), n = 5 (SCI/Vehicle), n = 5 (SCI/CR8).