Figure 2.

Extent of bilateral OFC lesion. A, This figure depicts photomicrographs of stained coronal sections through the area of the intended lesion in the three animals with OFC lesions (OFC1 to OFC3) alongside drawings of the intended extent of the lesions on drawings of representative coronal sections (left column). The top row shows reconstructions of the area of cortex lesioned on drawings of a representative ventral surface. Numerals indicate the distance in millimeters from the interaural plane. None of the OFC lesioned animals sustained any bilateral damage outside the area of the intended region; two animals, OFC2 and OFC3, sustained extremely slight unilateral damage beyond the intended lateral boundary of the lesion; and in all three animals the lesions did not extent as far medially as intended. B, Photomicrographs of stained coronal sections through the area of the intended lesion in the three animals with OFC lesions (OFC1 to OFC3). Numerals indicate the distance in millimeters from the interaural plane. The black arrows point to the most lateral and medial extent of the lesion in each section indicating that the lesion extent was limited to the intended orbitofrontal cortex. Extensive white matter can be seen to remain intact in the region just dorsal to and between the tips of these arrows.