Table 1.
Clinical characteristics of S. agalactiae invasive infections in non-pregnant adults 2004 – 2012
| Total Invasive infections n = 57 n (%) | Female n = 21 n (%) | Male n = 36 n (%) | Bloodstream Infections n = 34 n (%) | |
|---|---|---|---|---|
| Female | 21 (36.8) | 12 (35.3) | ||
| Male | 36 (63.2) | 22 (64.7) | ||
| ≥60 y.o | 25 (43.9) | 8 (38) | 15 (42) | 18 (53) |
| Mean | 53 y. o. | 55 y. o. | ||
| Range | [17–82] | [24–83] | ||
| In-hospital fatality | 10 (17.5) | 3 (14.3) | 6 (16.7) | 7 (20.6) |
| Polymicrobial infections | 13 (22.8) | 2 (9.5) | 11 (31) | 7 (20.6) |
| Bloodstream infections | 34 (59.7) | 12 (57.1) | 22 (61.1) | |
| Underlying conditions | ||||
| Cancer | 14 (24.6) | 8 (38) | 6 (16.7) | 10 (29.4) |
| -Hematologic malignancies | 7 (12.3) | 4 (19) | 3 (8.3) | 5 (14.7) |
| Diabetes | 16 (28) | 6 (28.6) | 10 (27.8) | 7 (20.6) |
| Transplant | 4 (7) | - | 2 (5.6) | 1 (2.9) |
| Cirrhosis/liver disorder | 4 (7) | 1 (4.8) | 3 (8.3) | 3 (8.8) |
| Renal disorder | 7 (12.3) | 1 (4.8) | 2 (5.6) | 3 (8.8) |
| Lung disease | 3 (5.3) | 2 (9.5) | 2 (5.6) | 2 (5.9) |
| HIV | 3 (5.3) | - | 3 (8.3) | 1 (2.9) |
| Autoimmune disorder | 3 (5.3) | 1 (4.8) | 1 (2.8) | 3 (8.8) |
| Other | 3 (5.3) | 2 (9.5) | 2 (5.6)* | 2 (5.9)** |
| More than one underlying condition | 20 (35) | 6 (28.6) | 14 (38.9) | 13 (38.2) |
| Portal of entry | ||||
| Primary bacteremia | 14 (41.2) | |||
| Skin and soft tissue | 8 (23.5) | |||
| Respiratory tract | 7 (20.6) | |||
| Gastrointestinal tract | 4 (11.8) | |||
| Urinary tract | 1 (2.9) |
y.o: years old.
*No underlying condition was identified in 5 cases.
**No underlying condition was identified in 2 bloodstream infections.