Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Solubility parameter calculation for drug polymer compatibility.
| Drug and polymers | δ hi | δ di | δ pi | δ | Δδ MPa1/2 (not ≥7) | Drug-polymer compatibility |
|---|---|---|---|---|---|---|
| PCZ | 9.04 | 3.11 | 15.93 | 18.57 (a) | — | — |
| Sol + PEG400 | (19.43 + 9.60)/2 | 14.51 (b) | (a − b) = 4.06 | Miscible | ||
| Sol + LF127 | (19.43 + 11.20)/2 | 15.31 (c) | (a − c) = 3.26 | Miscible | ||
| Sol + LF68 | (19.43 + 12.37)/2 | 15.9 (d) | (a − d) = 2.67 | Miscible | ||
| Sol + TPGS | (19.43 + 8.71)/2 | 14.07 (e) | (a − e) = 4.5 | Miscible | ||
