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Impact of hyperthermia on actin filament organization in HeLa cells expressing Cx43-EGFP under control conditions (a); after hyperthermia (6 h at 42°C) (b); under control conditions with XG-102 (4 μM) (c); after hyperthermia (6 h at 42°C) with XG-102 (4 μM) (d). Blue: F-actin labeled with Alexa Fluor 594 phalloidin; green: Cx43-EGFP; white arrows indicate annular junctions containing internalized GJ plaques. Scale bar 25 μm.
